Why the study?
Does 24-hour ambulatory blood pressure monitoring detect early changes in blood pressure and heart rate in normotensive adolescents with insulin-dependent diabetes mellitus compared to healthy controls?
Does 24-hour ambulatory blood pressure monitoring detect early changes in blood pressure and heart rate in normotensive adolescents with insulin-dependent diabetes mellitus compared to healthy controls?
Ambulatory blood pressure monitoring in normotensive adolescents with type 1 diabetes reveals elevated heart rates and a correlation between diabetes duration and diastolic blood pressure, suggesting early cardiovascular changes.
Supports early autonomic changes in normotensive type 1 diabetes adolescents; leaves open whether ambulatory monitoring refines risk stratification.
There is little information regarding ambulatory blood pressure in adolescents with insulin-dependent diabetes. Twenty-four-hour ambulatory blood pressure and heart rate was studied in 28 normotensive adolescents with insulin-dependent diabetes mellitus (IDDM) and normoalbuminuria, and adolescent controls. Ambulatory heart rate was higher during day and night (P = .001) in the IDDM patients, with normal mean diurnal variation of heart rate and blood pressure. Duration of diabetes related to diastolic ambulatory blood pressure (r = 0.69, P = .0001) and diastolic blood pressure burden (r = 0.61, P = .0001) independent of age, gender, height, body mass index, metabolic control, and albumin excretion rate. The ambulatory blood pressure monitor was well accepted in patients and controls. Ambulatory blood pressure monitoring in adolescents detects early changes in relation to duration of insulin-dependent diabetes.
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Khan et al. (1994) studied this question.
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