Why the study?
Does insulin daily dosage reduction reduce blood pressure and alter fluid/electrolyte balance in type II diabetic women taking excess insulin?
Population
n=12 type II diabetic women taking insulin doses over their need, including 6 with essential hypertension…
Comparison
Insulin daily dosage reduction. vs Baseline (prior to insulin reduction).
Design
Cohort
Follow-up
6 days
Authors
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May lower BP with insulin reduction in hypertensive type 2 diabetes; leaves open causality and practice change pending RCTs.
Does insulin daily dosage reduction reduce blood pressure and alter fluid/electrolyte balance in type II diabetic women taking excess insulin?
Reducing excess insulin dosage in type II diabetic women with hypertension leads to a significant decrease in blood pressure, body weight, and increased sodium excretion.
Tedde et al. (1989) studied this question.
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