Key result
Cardiac resynchronization therapy improves diastolic function in heart failure, though this effect appears dependent on concurrent improvements in systolic function.
Why the study?
Does cardiac resynchronization therapy improve left ventricular diastolic function in patients with heart failure?
Does cardiac resynchronization therapy improve left ventricular diastolic function in patients with heart failure?
Cardiac resynchronization therapy generally improves left ventricular diastolic function in heart failure, though this effect appears to be dependent on concurrent improvements in systolic function.
Answers are grounded in this paper and cite their sources.
Supports assessing systolic response when evaluating CRT diastolic effects in HF; leaves open prospective trials isolating independent diastolic benefits.
Cardiac resynchronization therapy (CRT) improves systolic performance in heart failure (HF). However, the effects of CRT on left ventricular diastolic function were variable and not fully understood. The available studies used different diastolic parameters derived from pulse and tissue Doppler techniques and more recently from deformation data. The most studies showed that CRT improves diastolic function (data are more controversial regarding relaxation) but this seems to be dependent on improvement in systolic function.
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Kammoun et al. (2015) conducted a review in Heart failure. Cardiac resynchronization therapy (CRT) was evaluated on Left ventricular diastolic function. Cardiac resynchronization therapy improves diastolic function in heart failure, though this effect appears dependent on concurrent improvements in systolic function.
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