Key result
Medications, OSA, primary aldosteronism, and CKD drive most secondary causes of resistant hypertension.
Population
Patients with resistant hypertension
Design
Review
Authors
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Supports screening for common secondary causes in resistant hypertension; leaves open prospective validation of impact on outcomes.
This review highlights the importance of identifying and managing secondary causes of resistant hypertension, such as NSAID use, obstructive sleep apnea, and primary aldosteronism, to improve blood pressure control.
Faselis et al. (2011) conducted a review in Resistant hypertension. Drug-induced hypertension (especially from NSAIDs), obstructive sleep apnea, primary aldosteronism, and chronic kidney disease represent the most common secondary causes of resistant hypertension.