Key result
Obesity (BMI >30 kg/m2) was associated with significantly higher odds of 30-day readmission (OR 1.775) compared to non-obese patients hospitalized with heart failure.
Why the study?
Obesity is an established risk factor for heart failure, but data regarding its independent association with mortality and morbidity remain heterogeneous.
Does obesity increase 30-day readmissions, in-hospital mortality, and the use of NIPPV in hospitalized heart failure patients?
Observational (n=800)
No
Does obesity increase 30-day readmissions, in-hospital mortality, and the use of NIPPV in hospitalized heart failure patients?
Effect estimate: OR 1.775 (95% CI 1.33-2.37)
Absolute Event Rate: 44% vs 30.7%
p-value: p=0.0001
In hospitalized heart failure patients, obesity (BMI >30 kg/m²) is an independent risk factor for 30-day readmissions and increased requirement for noninvasive positive pressure ventilation.
The prevalence of heart failure (HF) is on the rise; currently, it affects around five million people in the United States (US) and the prevalence is expected to rise from 2.42% in 2012 to 2.97% in 2030. HF is a leading cause of hospitalizations and readmissions, accounting for a major economic burden to the US healthcare system. Obesity is a widely accepted risk factor of HF; however, data regarding its independent association with HF mortality and morbidity is heterogeneous. Globally, more than two-thirds of deaths attributable to high body mass index (BMI) are due to cardiovascular diseases (CVD). This study aimed to investigate the potential role of obesity (BMI >30 Kg/m 2 ) in HF patients in terms of 30-day readmissions, in-hospital mortality, and the use of noninvasive positive pressure ventilation (NIPPV).
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Mughal et al. (2021) conducted an observational in Heart Failure (n=800). Obesity (BMI >30 kg/m2) vs. Non-obese (BMI <30 kg/m2) was evaluated on 30-day readmission (OR 1.775, 95% CI 1.33-2.37, p=0.0001). Obesity (BMI >30 kg/m2) was associated with significantly higher odds of 30-day readmission (OR 1.775) compared to non-obese patients hospitalized with heart failure.
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