Why the study?
Does extraperitoneal wound drainage and prophylactic systemic cephaloridine reduce postoperative wound infection in patients undergoing appendicectomy?
Population
246 patients undergoing appendicectomy at the Leicester Royal Infirmary
Comparison
Extraperitoneal wound drainage and/or a 3-day… vs Control
Design
RCT, randomized
Authors
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Supports prophylactic cephaloridine plus drainage in appendicectomy; reinforces combined prevention in contaminated abdominal surgery.
Does extraperitoneal wound drainage and prophylactic systemic cephaloridine reduce postoperative wound infection in patients undergoing appendicectomy?
Both extraperitoneal wound drainage and prophylactic cephaloridine, particularly when combined, significantly reduce the incidence of postoperative wound infections following appendicectomy for gangrenous or perforated appendicitis.
Everson et al. (1977) studied this question.
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