Why the study?
CRT with an additional His bundle lead had only been reported in a few case reports and small series for patients with permanent AF refractory to other therapies.
Does ICD/CRT with His bundle pacing improve left ventricular function and clinical symptoms in patients with permanent atrial fibrillation, heart failure, and bundle branch block?
Population
14 consecutive patients with permanent AF, HF, BBB with QRS >130 ms, and impaired LVEF
Comparison
ICD/CRT systems with His bundle pacing
Design
Consecutive case series
Follow-up
Mean 14.4 months
Authors
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His bundle pacing shows promise in permanent AF-HF; extends limited case data but leaves open need for randomized confirmation.
Does ICD/CRT with His bundle pacing improve left ventricular function and clinical symptoms in patients with permanent atrial fibrillation, heart failure, and bundle branch block?
His bundle pacing combined with ICD/CRT significantly improves left ventricular ejection fraction, reduces ventricular dimensions, and improves NYHA functional class in patients with permanent atrial fibrillation, heart failure, and bundle branch block.
Boczar et al. (2019) studied this question.
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