Why the study?
Does staged heart transplantation and subsequent chemotherapy improve survival in patients with severe cardiac light-chain amyloidosis?
Does staged heart transplantation and subsequent chemotherapy improve survival in patients with severe cardiac light-chain amyloidosis?
Staged heart transplantation followed by chemotherapy and stem cell transplantation is a feasible and potentially successful treatment option for highly selected patients with advanced cardiac light-chain amyloidosis.
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Supports feasibility of staged transplantation in highly selected cardiac AL amyloidosis; leaves open prospective confirmation of survival benefit.
Kristen et al. (2009) studied this question.
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