Highlights orthotopic heart transplantation as a successful definitive treatment for fulminant giant cell myocarditis.
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Case supports transplant for fulminant giant cell myocarditis; leaves open need for prospective data before practice change.
Myocarditis is a major cause of end-stage heart failure and is responsible for up to 10% of cases of idiopathic dilated cardiomyopathy. Giant cell myocarditis is a particularly fulminant disease that has a poor response to immunosuppressive therapy. Cardiac transplantation is the definitive treatment.
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Miranda et al. (2017) studied this question.
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