Describes a successful technique for selective catheterization of individual coronary arteries in intact dogs, enabling intracoronary injections of pharmacologic agents or radio-opaque materials.
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Technique enables targeted intracoronary delivery in canine models; leaves open translation to human selective interventions.
A technic is described for selective catheterization of individual coronary arterial branches in intact dogs by means of special catheters which permit intracoronary injections of pharmacologic agents or radio-opaque materials. All the main coronary arteries (right, left anterior descending, left circumflex) have been successfully catheterized and injected, both alone and in combination.
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West et al. (1958) studied this question.
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