Key result
Morning blood pressure surge in newly diagnosed, untreated hypertensive patients was associated with significantly impaired 3D left ventricular longitudinal strain compared to non-surge patients (-30.1 vs -31.1, p=0.045).
Why the study?
The study was conducted to examine left ventricular function using 3D speckle tracking echocardiography in untreated, newly diagnosed hypertensive patients according to morning blood pressure surge status.
Does morning blood pressure surge impair left ventricular mechanics assessed by 3D speckle tracking echocardiography in newly diagnosed, untreated hypertensive patients?
Cross-Sectional (n=163)
No
Does morning blood pressure surge impair left ventricular mechanics assessed by 3D speckle tracking echocardiography in newly diagnosed, untreated hypertensive patients?
Morning blood pressure surge is associated with impaired left ventricular mechanics on 3D speckle tracking echocardiography in newly diagnosed, untreated hypertensive patients, even when conventional 2D echocardiography shows no differences.
Answers are grounded in this paper and cite their sources.
Morning surge associated with impaired 3D LV strain in untreated hypertensives; hypothesis-generating, longitudinal studies needed before clinical adoption.
BACKGROUND: The aim of this study was to examine left ventricular (LV) function in untreated, newly diagnosed hypertensive patients with morning blood pressure surge (MBPS) status using three-dimensional (3D) speckle tracking echocardiography (STE). METHODS: In this study, 163 newly diagnosed hypertensive patients were included, and all patients underwent 24-h ambulatory blood pressure monitoring (ABPM). According to ABPM, participants were divided into a MBPS group and a non-MBPS group. The entire study population was examined by complete two-dimensional (2D) transthoracic echocardiography (TTE) and 3D STE. RESULT: The results of this study showed that 3D LV longitudinal strain was significantly decreased in the MBPS group compared with the non-MBPS group (- 30.1 ± 2.0 vs. -31.1 ± 2.7, p = 0.045). Similar trends were observed for 3D twist (9.6 ± 6.1 vs. 12.1 ± 4.8, p = 0.011) as well as for 3D torsion (1.23 ± 0.78 vs. 1.49 ± 0.62, p = 0.042). The LV principal strain was decreased in the MBPS group (- 33.9 ± 1.7 vs. -35.5 ± 2.8, p < 0.001). The 3D LV global longitudinal strain (GLS) and principal strain were significantly associated with quartile of MBPS as measured by systolic blood pressure (SBP). CONCLUSION: The 3D STE revealed that LV mechanics were more impaired in the MBPS group than in the non-surge newly diagnosed, untreated hypertensive patients; even the 2D TTE parameters showed no difference.
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Kwon et al. (2021) conducted a cross-sectional in Newly diagnosed, untreated hypertension (n=163). Morning blood pressure surge (MBPS) vs. Non-MBPS was evaluated on 3D left ventricular longitudinal strain (p=0.045). Morning blood pressure surge in newly diagnosed, untreated hypertensive patients was associated with significantly impaired 3D left ventricular longitudinal strain compared to non-surge patients (-30.1 vs -31.1, p=0.045).
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