Key result
Signal-averaged vector-projected 187-channel ECG-based risk stratification successfully guided amiodarone therapy for electrical storm, with no VT recurrence at 2 years.
Why the study?
Does SAVP-ECG-based risk stratification help guide antiarrhythmic therapy in a patient with electrical storm after CRT-D implantation?
Case Report (n=1)
Does SAVP-ECG-based risk stratification help guide antiarrhythmic therapy in a patient with electrical storm after CRT-D implantation?
SAVP-ECG-based risk stratification using RTc and Tpeak-end dispersion may be a useful tool for guiding antiarrhythmic therapy in patients experiencing electrical storm.
Answers are grounded in this paper and cite their sources.
May guide amiodarone in post-CRT-D electrical storm; leaves open prospective validation of SAVP-ECG stratification.
We describe treatment of atrial flutter and electrical storm presenting as incessant ventricular tachycardia (VT) after implantation of a cardiac resynchronization therapy defibrillator (CRT‐D) in a patient with dilated cardiomyopathy. No prior arrhythmic event had occurred. Our treatment strategy, including amiodarone administration, was guided in part by signal‐averaged vector‐projected 187‐channel electrocardiogram (SAVP‐ECG)‐based risk stratification for ventricular arrhythmia. Corrected recovery time (RTc) dispersion and Tpeak‐end dispersion were used to evaluate transmural dispersion of repolarization. RTc and Tpeak‐end dispersion increased during the period of electrical storm. Values were improved 2 years after CRT‐D implantation, and the amiodarone was discontinued. The VT has not recurred despite discontinuation of the antiarrhythmic agent. SAVP‐ECG‐based risk stratification for ventricular arrhythmia proved useful for the management of antiarrhythmic therapy.
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Nakai et al. (2013) conducted a case report in Dilated cardiomyopathy with electrical storm after CRT-D implantation (n=1). Amiodarone guided by signal-averaged vector-projected 187-channel electrocardiogram (SAVP-ECG) was evaluated. Signal-averaged vector-projected 187-channel ECG-based risk stratification successfully guided amiodarone therapy for electrical storm, with no VT recurrence at 2 years.
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