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February 25, 2011European Journal of Cardiovascular Prevention & RehabilitationOpen Access

Effects of walking on heart rate recovery, endothelium modulators and quality of life in patients with heart failure

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Key result

A 12-week unsupervised walking programme significantly improved heart rate recovery (p < 0.001) and perceived quality of life (p < 0.02) in patients with chronic heart failure.

Why the study?

Does a 12-week unsupervised walking programme improve heart rate recovery, endothelial modulators, and quality of life in patients with chronic heart failure?

Population

28 stabilized chronic heart failure patients of NYHA class II and III, and 10 age-matched healthy volunteers.

Comparison

12-week unsupervised walking programme… vs Non-exercise group (n=10).

Design

Cohort

Follow-up

12 weeks

Authors

KTKonstantinos TsarouhasUniversity Hospital of LarissaCKChristina KaratzaferiUniversity of ThessalyCTChristina TsitsimpikouState Laboratory

Discussion

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Overview

Supports unsupervised walking benefits in chronic HF; hypothesis-generating, needs RCTs before practice change.

Study Design

Type

Cohort (n=38)

Structured PICO

Does a 12-week unsupervised walking programme improve heart rate recovery, endothelial modulators, and quality of life in patients with chronic heart failure?

P
Population
28 stabilized chronic heart failure (CHF) patients of NYHA class II and III, and 10 age-matched healthy volunteers.
I
Intervention
12-week unsupervised walking programme consisting of 40-minute walking for five days per week.
C
Comparator
Non-exercise group (n=10).
O
Outcome
Heart rate recovery (HRR), serum modulators of endothelial function (ADMA and homocysteine), markers of inflammation and oxidative stress, and quality of life measures (SF-36 and Zung depression scale).surrogate

Main Result

p-value: p=<0.001

A 12-week unsupervised walking program improves heart rate recovery, attenuates endothelial damage markers, and enhances perceived quality of life in patients with chronic heart failure.

Cite This Study

Tsarouhas et al. (2011) conducted a cohort in Chronic heart failure (CHF) (n=38). Unsupervised walking programme vs. Non-exercise was evaluated on Heart rate recovery (HRR), serum modulators of endothelial function, markers of inflammation and oxidative stress, and quality of life measures (p=<0.001). A 12-week unsupervised walking programme significantly improved heart rate recovery (p < 0.001) and perceived quality of life (p < 0.02) in patients with chronic heart failure.

synapsesocial.com/papers/6a1dd2be49e88a0d41602f9ehttps://doi.org/10.1177/1741826710397099
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function.1992 · 954 citations
  2. 2Circadian pattern of heart rate variability in chronic heart failure patients Effects of physical training1995 · 105 citations
  3. 3Asymmetric Dimethylarginine Enhances Cardiovascular Risk Prediction in Patients With Chronic Heart Failure2007 · 106 citations
  4. 4Using Pedometers to Increase Physical Activity and Improve Health2007 · 2,114 citations
  5. 5Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction1998 · 1,199 citations