What does this research mean for the field?

Hypertension is a significant risk factor for early atherosclerosis and endothelial dysfunction in Japanese patients, characterized by persistent endothelial damage and inflammation even when blood pressure is well-controlled. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2002Hypertension ResearchOpen Access

Association of Cardiovascular Risk Factors and Endothelial Dysfunction in Japanese Hypertensive Patients: Implications for Early Atherosclerosis.

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Why the study?

Does hypertension associate with endothelial dysfunction and early atherosclerosis in Japanese patients?

Population

Japanese normotensive and hypertensive patients under treatment

Comparison

Hypertension and accumulation of cardiovascular… vs Normotensive patients

Design

Cross-sectional

Authors

TFTomoo FurumotoHokkaido University NSNaotaka SaitoHakodate Central General Hospital JDJie DongCentral South University

Discussion

Member takes

Implication

Persistent endothelial dysfunction may persist despite BP control; hypothesis-generating for vascular-targeted strategies in Japanese hypertensives.

Structured PICO

Does hypertension associate with endothelial dysfunction and early atherosclerosis in Japanese patients?

Population

Japanese normotensive and hypertensive patients under treatment

Intervention

Hypertension and accumulation of cardiovascular risk factors

Comparator

Normotensive patients

Outcome

Flow-mediated dilation (FMD) of the brachial arterysurrogate

Cite This Study

Furumoto et al. (2002) studied this question.

synapsesocial.com/papers/6a1e9b5d544bdf605faf1402 https://doi.org/10.1291/hypres.25.475

Topics

Hypertension management

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Implication

Persistent endothelial dysfunction may persist despite BP control; hypothesis-generating for vascular-targeted strategies in Japanese hypertensives.

Association of Cardiovascular Risk Factors and Endothelial Dysfunction in Japanese Hypertensive Patients: Implications for Early Atherosclerosis.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Association of Cardiovascular Risk Factors and Endothelial Dysfunction in Japanese Hypertensive Patients: Implications for Early Atherosclerosis.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider