Population
Male rat adrenals
Comparison
Low sodium diet vs Normal diet (controls)
Design
Preclinical
Authors
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Offers no immediate clinical implications; extends rodent data on AT1 regulation but leaves open human relevance.
Sodium restriction increases the expression and binding capacity of AT1 and AT2 receptors in the rat adrenal gland, highlighting their role in adrenal adaptation to physiological stimulation.
Lehoux et al. (1997) studied this question.
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