Key result
New ST-segment depression after dipyridamole infusion was highly specific (89.5%) but had low sensitivity (20.2%) for the diagnosis of ischemia on myocardial perfusion SPECT.
Why the study?
Do ECG changes after dipyridamole infusion predict ischemia in patients undergoing myocardial perfusion SPECT?
Population
200 patients undergoing 2-day dipyridamole stress/rest Tc-99m-sestamibi myocardial perfusion SPECT
Design
Cross-sectional
Authors
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ST depression after dipyridamole may aid ruling in ischemia clinically; leaves open its adjunctive value beyond SPECT.
Cross-Sectional (n=200)
Do ECG changes after dipyridamole infusion predict ischemia in patients undergoing myocardial perfusion SPECT?
ST-segment depression after dipyridamole infusion is a highly specific but poorly sensitive marker for ischemia on myocardial perfusion SPECT.
Zakavi et al. (2010) conducted a cross-sectional in Patients undergoing myocardial perfusion imaging (n=200). Dipyridamole infusion was evaluated on Diagnosis of ischemia (reversible defects on SPECT). New ST-segment depression after dipyridamole infusion was highly specific (89.5%) but had low sensitivity (20.2%) for the diagnosis of ischemia on myocardial perfusion SPECT.
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