Key result
Intermittent hypoxia is independently associated with dyslipidemia, but the role of obstructive sleep apnea in the causality of dyslipidemia remains to be established.
Why the study?
Does obstructive sleep apnea and intermittent hypoxia cause dyslipidemia?
Population
Patients with obstructive sleep apnea (OSA) and animal models (lean mice) exposed to intermittent hypoxia
Design
Review
Authors
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No change to dyslipidemia care from OSA status; leaves open causality of intermittent hypoxia in humans.
Does obstructive sleep apnea and intermittent hypoxia cause dyslipidemia?
While animal models show intermittent hypoxia induces hyperlipidemia, definitive evidence establishing a causal role of OSA in human dyslipidemia is still lacking.
Drager et al. (2010) conducted a review in Obstructive sleep apnea and dyslipidemia. Obstructive sleep apnea and intermittent hypoxia was evaluated on Dyslipidemia. Intermittent hypoxia is independently associated with dyslipidemia, but the role of obstructive sleep apnea in the causality of dyslipidemia remains to be established.
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