Key result
Amrinone infusions demonstrated no direct positive inotropic effect, with haemodynamic changes predominantly resulting from vasodilatation.
Why the study?
Do intracoronary and intravenous amrinone infusions improve haemodynamics in patients with cardiac failure and near normal cardiac function?
Population
Patients with cardiac failure and patients with near normal cardiac function
Design
Other
Authors
Loading...
Amrinone's effects in heart failure are driven by vasodilatation; leaves open its comparative value versus selective vasodilators.
Do intracoronary and intravenous amrinone infusions improve haemodynamics in patients with cardiac failure and near normal cardiac function?
Amrinone's haemodynamic benefits in heart failure are predominantly due to peripheral vasodilatation rather than direct positive inotropic effects.
Wilmshurst et al. (1985) studied Cardiac failure and near normal cardiac function. Amrinone infusions (intracoronary and intravenous) was evaluated on Haemodynamic effects (contractility, cardiac output, filling pressures). Amrinone infusions demonstrated no direct positive inotropic effect, with haemodynamic changes predominantly resulting from vasodilatation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: