Key result
Cigarette smoking in patients without heart disease resulted in a significant rise in coronary blood flow and heart rate, and a significant decline in coronary vascular resistance.
Why the study?
Does cigarette smoking alter coronary blood flow and myocardial metabolism in patients without heart disease?
Observational
Does cigarette smoking alter coronary blood flow and myocardial metabolism in patients without heart disease?
Acute cigarette smoking in patients without heart disease increases coronary blood flow and decreases coronary vascular resistance, showing no evidence of acute coronary constriction.
Answers are grounded in this paper and cite their sources.
Indicates no acute coronary constriction from smoking; leaves open translation to outcomes and metabolism in larger studies.
The effect of smoking on the heart has been a controversial subject. The present studies were undertaken to investigate the effect of cigarette smoking on the coronary flow, myocardial usage of oxygen and myocardial extraction of glucose, pyruvate, lactate, and ketones. Catheterization of the coronary sinus revealed that cigarette smoking in patients without heart disease results in a significant rise in coronary blood flow and heart rate and a significant decline in coronary vascular resistance and myocardial extraction of oxygen and glucose. No evidence of coronary vascular constriction was detected.
No takes yet. Share an insight, caveat, or question.
Bargeron et al. (1957) conducted an observational in Without heart disease. Cigarette smoking was evaluated on Coronary blood flow, heart rate, coronary vascular resistance, and myocardial extraction of oxygen and glucose. Cigarette smoking in patients without heart disease resulted in a significant rise in coronary blood flow and heart rate, and a significant decline in coronary vascular resistance.
Synapse has enriched 10 related papers. Consider them for comparative context: