Key result
Surgical production of complete heart block in dogs acutely reduced cardiac output, coronary flow, and mean arterial pressure, with myocardial hypertrophy developing between 2 and 18 days.
Authors
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Acute hemodynamic effects in experimental heart block support urgent pacing; leaves open hypertrophy mechanisms in humans.
Starzl et al. (1955) studied Acute complete heart block. Surgical production of complete heart block vs. Preoperative baseline was evaluated on Hemodynamic parameters and myocardial changes. Surgical production of complete heart block in dogs acutely reduced cardiac output, coronary flow, and mean arterial pressure, with myocardial hypertrophy developing between 2 and 18 days.
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