Key result
Salt restriction plays an important role in managing hypertension and preventing target organ damage in patients with chronic kidney disease, though both excessively high and low sodium intake can cause adverse effects.
Why the study?
Does salt restriction prevent hypertension and target organ damage in patients with renal disease?
Does salt restriction prevent hypertension and target organ damage in patients with renal disease?
This review emphasizes the importance of salt restriction in managing hypertension and preventing target organ damage in patients with renal disease.
Supports moderate salt restriction in pediatric CKD hypertension; leaves optimal intake thresholds open for prospective trials.
The importance of salt restriction in the treatment of patients with renal disease has remained highly controversial. In the following we marshal the current evidence that salt plays a definite role in the genesis of hypertension and target organ damage, point to practical problems of salt restriction, and report on novel pathomechanisms of how salt affects blood pressure and causes target organ damage.
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Ritz et al. (2008) conducted a review in Chronic kidney disease and hypertension. Salt restriction vs. High salt intake was evaluated. Salt restriction plays an important role in managing hypertension and preventing target organ damage in patients with chronic kidney disease, though both excessively high and low sodium intake can cause adverse effects.
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