Key result
Women undergoing percutaneous coronary intervention between 2012 and 2016 had a 31% lower risk of in-hospital mortality compared to those treated between 2006 and 2008 (OR 0.69).
Why the study?
Temporal trends and in-hospital results in women undergoing percutaneous coronary intervention needed evaluation across different time frames using national registry data.
Does percutaneous coronary intervention in women show improved procedural success and reduced in-hospital complications over a 10-year period?
Observational (n=59,931)
Yes
Does percutaneous coronary intervention in women show improved procedural success and reduced in-hospital complications over a 10-year period?
Odds Ratio: 0.69 (95% CI 0.54–0.88)
Absolute Event Rate: 1% vs 1.3%
p-value: p=0.0026
Over a 10-year period, women undergoing PCI experienced increasing procedural success and decreasing in-hospital complications, reflecting advancements in interventional techniques and devices.
Supports temporal outcome improvements for women undergoing PCI; leaves open whether technique advances explain the association.
Background: Temporal trends in the female population submitted to percutaneous coronary intervention were evaluated as to clinical, angiographic and procedural aspects, based on analysis of 10-year results of a national registry. The objective of this study was to compare the in-hospital results and clinical outcomes by grouping the sample into three different time frames. Methods: The database used was the Central Nacional de Intervenes Cardiovasculares (CENIC). A total of 59,931 women undergoing percutaneous coronary intervention between 2006 and 2016 were assessed and divided into timeframes, analyzing clinical and angiographic variables, as well as in-hospital outcomes. Results: There was a decrease in prevalence of smoking, hypertension, and dyslipidemia over time. Likewise, the prevalence of calcified lesions, thrombotic lesions and bifurcations decreased. The success of the procedure increased and there was a decrease in post-procedure complications, such as death, infarction or emergency surgical revascularization. In the analysis of predictors of risk of death, patients with left main coronary artery lesion presented a 15-fold risk of death (p<0.0001), and multi-vessel lesions increased the risk approximately three times (p<0.0001). Conclusion: Percutaneous coronary intervention in women presented better results along the analyzed period, with higher procedural success rates and lower rates of in-hospital complications.
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Ferreira et al. (2019) conducted an observational in Coronary artery disease undergoing percutaneous coronary intervention (n=59,931). Percutaneous coronary intervention in recent period (2012-2016) vs. Percutaneous coronary intervention in earlier period (2006-2008) was evaluated on In-hospital mortality (OR 0.69, 95% CI 0.54-0.88, p=0.0026). Women undergoing percutaneous coronary intervention between 2012 and 2016 had a 31% lower risk of in-hospital mortality compared to those treated between 2006 and 2008 (OR 0.69).
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