Key result
Women face higher mortality than men after PCI for ACS driven by age and comorbidities.
Why the study?
Disparities persist in the diagnosis, management, and outcomes of ischemic heart disease in women compared to men, motivating a review of factors driving sex-based differential PCI outcomes.
Design
Review
Authors
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May warrant sex-specific PCI strategies in women; extends evidence on hormonal influences on coronary disease.
This review highlights the distinct pathophysiology, higher comorbidity burden, and worse outcomes of ischemic heart disease and percutaneous coronary interventions in women, emphasizing the need for sex-specific awareness and trial representation.
Joodi et al. (2023) conducted a review in Acute coronary syndrome and ischemic heart disease. Percutaneous Coronary Intervention vs. Men was evaluated. Women undergoing percutaneous coronary intervention for acute coronary syndromes experience higher short- and long-term mortality compared to men due to older age, comorbidities, and distinct vascular biology.
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