Retrospective cohort study evaluates AISI for mortality prediction in palliative care, indicating enhanced care planning.
Key Points
This study aims to evaluate the prognostic value of the Aggregate Index of Systemic Inflammation (AISI) in palliative care patients.
Retrospective cohort study of 144 palliative care patients admitted between January 2020 and December 2024.
Prognostic performance of AISI, SIRI, SII, and NLR was assessed for predicting mortality and critical care needs.
Statistical analyses included receiver operating characteristic curve, multivariable Cox regression, and Kaplan-Meier survival analysis.
AISI had the highest discriminatory capacity for mortality prediction (AUC 0.826, 95% CI 0.754–0.898), significantly superior to NLR and SII (p < 0.042).
Patients with AISI > 1850 had a median survival of 9 days compared to 35 days for those with AISI ≤ 1850 (log-rank p < 0.001).
AISI also predicted ICU admission (adjusted OR 3.96, 95% CI 1.89–8.28, p < 0.001) and mechanical ventilation requirement (adjusted OR 4.15, 95% CI 1.98–8.69, p < 0.001).