The diameter of the MEF1 poliomyelitis virus is determined to be 21 mμ when frozen-dried or packed in a crystalline array, which is considered the more reliable measurement compared to air-drying.
Supports 21 mμ as reliable MEF1 virus diameter; leaves open validation with modern imaging.
SummaryThe particles of the MEF1 poliomyelitis virus, grown in monkey-kidney tissue culture, and subsequently purified by chemical and physical means, are spherical in shape and highly uniform in diameter. The diameter of individual particles, prepared by normal air-drying from a 0.1 M ammonium acetate suspension, is found to be 31 mμ. The diameter of particles packed in a crystalline array, or frozen-dried from a 0.1 M ammonium bicarbonate suspension, is found to be 21 mμ. It is believed that the latter diameter is the more significant and reliable figure.
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Schwerdt et al. (1954) studied this question.
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