Why the study?
Does red ginseng acidic polysaccharide reduce serum triglycerides and non-esterified fatty acids in hyperlipidemic rat models?
Population
120 male Sprague-Dawley rats with hyperlipidemia acutely induced by Triton WR1339 or corn oil
Comparison
Red ginseng acidic polysaccharide 100, 300, 500… vs Control group receiving hyperlipidemia inducer…
Design
Preclinical, randomized into six groups
Follow-up
3 days
Authors
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Hypothesis-generating for RGAP in hyperlipidemia; leaves open translation to human therapy.
Does red ginseng acidic polysaccharide reduce serum triglycerides and non-esterified fatty acids in hyperlipidemic rat models?
Red ginseng acidic polysaccharide reduces serum triglycerides and non-esterified fatty acids in hyperlipidemic rat models, potentially through the up-regulation of lipoprotein lipase activity.
Kwak et al. (2010) studied this question.
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