Key result
Supplementation with red ginseng and fermented red ginseng significantly reduced body weight gain, visceral adiposity, and improved lipid and inflammatory profiles in high-fat-fed rats.
Why the study?
Obesity carries risk for metabolic complications, prompting investigation into whether red ginseng and fermented red ginseng could protect against high-fat diet-induced metabolic disturbances in rats.
Does red ginseng and fermented red ginseng supplementation improve obese phenotypes, lipid profiles, inflammation, and antioxidant defense in high-fat diet-fed rats?
Population
Male Sprague-Dawley rats (n = 8/group, 6 weeks old)
Comparison
HF diet with RG vs HF with FRG vs unsupplemented HF diet vs LF diet
Design
Animal experimental study counterbalanced by initial weight
Follow-up
6 weeks
Authors
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Should not change clinical practice; hypothesis-generating for red ginseng in diet-induced metabolic disease.
Does red ginseng and fermented red ginseng supplementation improve obese phenotypes, lipid profiles, inflammation, and antioxidant defense in high-fat diet-fed rats?
p-value: p=<0.05
Red ginseng and fermented red ginseng supplementation effectively protects against high-fat diet-induced metabolic disturbances, including obesity, dyslipidemia, and inflammation, in a rat model.
Jeong et al. (2021) studied Diet-induced obesity (n=32). Red ginseng (RG) and fermented red ginseng (FRG) vs. High-fat diet without supplementation was evaluated on Body weight gain and visceral adiposity (p=<0.05). Supplementation with red ginseng and fermented red ginseng significantly reduced body weight gain, visceral adiposity, and improved lipid and inflammatory profiles in high-fat-fed rats.
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