Population
Mouse plasma (in vitro) and nephrectomized rat (in vivo)
Comparison
Generation of angiotensin I via mouse… vs Synthetic [Val5] and [Ile5] angiotensin I, II…
Design
Preclinical
Authors
Loading...
Supports [Ile5] angiotensin identity in mice matching humans; extends rodent model validity for renin-angiotensin research.
Mouse and rat angiotensins are of the [Ile5] type, similar to human angiotensins, which is important for experimental models of the renin-angiotensin system.
Jacobsen et al. (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: