Key result
Preclinical models of pressure-overload induced right ventricular remodeling highlight the importance of translational research in understanding the transition from compensated RV to failure.
This review emphasizes the significance of reliable pressure-volume measurements and molecular analyses in preclinical models to understand right ventricular remodeling and failure in pulmonary hypertension.
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Should not change PH management; leaves open targeted translational studies of RV transition to failure.
Pokreisz et al. (2007) conducted a review in Pressure-overload induced right ventricular remodeling. Preclinical models of pressure-overload was evaluated. Preclinical models of pressure-overload induced right ventricular remodeling highlight the importance of translational research in understanding the transition from compensated RV to failure.
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