Why the study?
Does antioxidant therapy or ACE inhibition improve mesenteric collateral growth in spontaneously hypertensive rats?
Does antioxidant therapy or ACE inhibition improve mesenteric collateral growth in spontaneously hypertensive rats?
Antioxidant therapies, including captopril, can reverse impaired collateral artery growth in spontaneously hypertensive rats, likely due to antioxidant properties rather than ACE inhibition alone.
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Antioxidant effects may aid collateral expansion in hypertensive rat models; leaves open human translation and ACE inhibitor specificity.
Miller et al. (2007) studied this question.
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