Key result
Bovine aortic endothelial cells exposed to fluid shear stress for 72 hours relaxed their shape in about 20 hours after cessation, though vestiges of the original orientation remained at 72 hours.
Population
Bovine aortic endothelial cells grown on glass coverslips
Comparison
Exposure to fluid shear stress for 72 hours… vs Unstressed control cells
Design
Preclinical
Follow-up
72 hours
Authors
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In vitro bovine endothelial relaxation after shear warrants no clinical change; leaves open in vivo human translation.
Bovine aortic endothelial cells exposed to fluid shear stress relax their elongated shape within 20 hours of returning to static conditions, though some orientation vestiges remain at 72 hours.
Remuzzi et al. (1984) studied this question. Fluid shear stress followed by cessation vs. Unstressed control cells was evaluated on Cell shape relaxation (loss of elongated shape and change in cell direction). Bovine aortic endothelial cells exposed to fluid shear stress for 72 hours relaxed their shape in about 20 hours after cessation, though vestiges of the original orientation remained at 72 hours.
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