The Relationship Between Visit-to-Visit Variability in Systolic Blood Pressure and All-Cause Mortality in the General Population
Why the study?
Does higher visit-to-visit variability in systolic blood pressure increase the risk of all-cause mortality in the general adult population?
Population
956 US adults ≥ 20 years of age from the Third National Health and Nutrition Examination Survey
Comparison
Higher visit-to-visit variability in systolic… vs Lower visit-to-visit variability in systolic…
Design
Cohort
Follow-up
median 14 years
Authors
Discussion
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Member takes
Implication
Supports SBP variability-mortality link in adults; leaves open whether reducing variability improves outcomes.
Structured PICO
Does higher visit-to-visit variability in systolic blood pressure increase the risk of all-cause mortality in the general adult population?
P
Population
956 US adults ≥ 20 years of age from the Third National Health and Nutrition Examination Survey
I
Intervention
Higher visit-to-visit variability in systolic blood pressure (standard deviation of 4.80 to 8.34 mm Hg and ≥ 8.35 mm Hg across 3 visits)
C
Comparator
Lower visit-to-visit variability in systolic blood pressure (standard deviation <4.80 mm Hg across 3 visits)
O
Outcome
All-cause mortalityhard clinical
In a population-based study of US adults, higher short-term visit-to-visit variability in systolic blood pressure was significantly associated with increased all-cause mortality over a median 14-year follow-up.
Cite This Study
Muntner et al. (2011) studied this question.