Key result
This review highlights the mechanistic and therapeutic differences in heart failure between patients of European origin and major ethnic minority groups in the UK.
Highlights the critical need to consider ethnic differences in heart failure etiology and treatment, as evidence from predominantly white trial populations may not be generalizable.
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Ethnic differences in UK HF care warrant caution with white-trial data; leaves open dedicated subgroup validation.
Heart failure is a major public health problem in the Western world. Aetiological factors involved in its development include hypertension, diabetes, and ischaemic heart disease--all of which differ in prevalence, and possibly mechanism, between patients of differing ethnicity. Unfortunately, epidemiological and therapeutic trials have involved almost exclusively white populations, and evidence from these trials cannot necessarily be assumed to be generalisable to populations that include high proportions of patients from other ethnic origins. This review will discuss the mechanistic and therapeutic differences that exist in heart failure between those of European origin, and patients from the major ethnic minority groups of the UK.
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Sosin et al. (2004) conducted a review in Heart failure. Ethnicity was evaluated. This review highlights the mechanistic and therapeutic differences in heart failure between patients of European origin and major ethnic minority groups in the UK.
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