Why the study?
Does intravenous acetyl strophanthidin alter pulmonary blood volume and hemodynamics in patients with heart disease?
Population
23 patients with heart disease undergoing right and left heart catheterization
Comparison
Intravenous administration of acetyl… vs Baseline (before administration)
Design
Cohort
Follow-up
Acute (during catheterization)
Authors
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Supports passive pulmonary decongestion only via LVEDP reduction; leaves open direct pulmonary vascular effects of digitalis-like agents.
Does intravenous acetyl strophanthidin alter pulmonary blood volume and hemodynamics in patients with heart disease?
Acute digitalization improves LV performance but only reduces pulmonary blood volume passively when accompanied by a decrease in LV end-diastolic pressure, showing no active pulmonary vasomotor effects.
Murphy et al. (1971) studied this question.
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