Key result
Mild hypoxia reduced coronary circulation time in healthy anaesthetized dogs, apparently reflecting increased coronary flow.
Why the study?
Does mild hypoxia affect coronary circulation time in healthy anaesthetized dogs?
Does mild hypoxia affect coronary circulation time in healthy anaesthetized dogs?
Mild hypoxia reduces coronary circulation time in a canine model, indicating a physiological increase in coronary flow.
No immediate clinical implications; leaves open translation of hypoxia-induced coronary flow changes from canine models to humans.
Following coronary cinéangiography in healthy anaesthetized dogs, the time interval between initial arterial filling and initial coronary sinus visualization was determined. During mild hypoxia this coronary circulation time was reduced, apparently reflecting increased coronary flow. Some clinical implications of this finding are discussed.
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Semb et al. (1975) studied this question. Mild hypoxia reduced coronary circulation time in healthy anaesthetized dogs, apparently reflecting increased coronary flow.
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