Key result
Qiliqiangxin enhanced glycolysis at early time points and oxidative metabolism and mitochondrial biogenesis at 48 hours in H9C2 cardiomyocytes via PGC-1α activation.
Population
H9C2 cardiomyocytes
Design
Preclinical
Follow-up
up to 48 hours
Authors
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Hypothesis-generating for Qiliqiangxin in cardiomyocyte metabolism; leaves open clinical translation pending in vivo validation.
Qiliqiangxin enhances cardiomyocyte metabolism and mitochondrial biogenesis through the activation of PGC-1α in vitro.
Lin et al. (2015) studied this question. Qiliqiangxin (QLQX) was evaluated on Oxidative metabolism, glycolysis, and mitochondrial biogenesis. Qiliqiangxin enhanced glycolysis at early time points and oxidative metabolism and mitochondrial biogenesis at 48 hours in H9C2 cardiomyocytes via PGC-1α activation.
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