Why the study?
Is the A1166C variant of the AT1R gene associated with essential hypertension in Caucasian subjects with a strong family history?
Population
108 Caucasian subjects with essential hypertension, a strong family history, and early onset disease, along…
Comparison
A1166C variant of the angiotensin II type 1… vs Normotensive controls / AA or AC genotypes
Design
Case-control
Authors
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Supports A1166C association in familial hypertension; leaves open clinical utility and need for replication.
Is the A1166C variant of the AT1R gene associated with essential hypertension in Caucasian subjects with a strong family history?
The A1166C variant of the AT1R gene is significantly associated with essential hypertension in Caucasian subjects with a strong family history.
Wang et al. (1997) studied this question.
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