Why the study?
Can time-domain analysis using correlation waveform analysis of intracardiac electrograms discriminate ventricular tachycardia from ventricular fibrillation?
Can time-domain analysis using correlation waveform analysis of intracardiac electrograms discriminate ventricular tachycardia from ventricular fibrillation?
Time-domain analysis using correlation waveform analysis of intracardiac electrograms can effectively discriminate between sinus rhythm, ventricular tachycardia, and ventricular fibrillation.
Supports CWA feasibility for VT/VF discrimination in isolated cases; leaves open prospective validation before clinical adoption.
To determine whether ventricular tachycardia (VT) and ventricular fibrillation (VF) can be discriminated by time-domain analysis, correlation waveform analysis (CWA) was performed using bipolar intracardiac electrograms of 12 consecutive patients during sinus rhythm (SR) and induced monomorphic VT and VF. Using a best fit template-signal alignment, CWA separated SR from 10/12 VTs (83%) and 12/12 VFs (100%), respectively. The individual variances for VT and VF were significantly different, and a threshold midway between the average variance in VT and VF was a successful discriminant in 11/12 cases (92%). These results suggest that time-domain analysis can discriminate VT and VF from SR, and the magnitude of the variance in VT and VF can be used to distinguish VT from VF.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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DiCarlo et al. (2002) studied this question.
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