Key result
Sympathetic nervous activity was significantly related to blood pressure in women (37 vs 25 bursts/min, P<0.001) and to body mass index in men, with weight loss reducing MSNA only in men.
Why the study?
Does the relationship between sympathetic nervous activity, body mass index, and blood pressure differ between men and women?
Population
167 age-matched normotensive and hypertensive men and women divided into three subgroups: lean, overweight…
Comparison
12-week diet vs Men vs. women; normotensive vs. hypertensive…
Design
Cross-sectional
Follow-up
12 weeks (for diet subgroup)
Authors
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Sex differences in sympathetic drivers of BP and BMI suggest tailored assessment; leaves open whether sex-specific interventions improve outcomes.
Observational (n=167)
Does the relationship between sympathetic nervous activity, body mass index, and blood pressure differ between men and women?
Absolute Event Rate: 37% vs 25%
p-value: p=<0.001
There are significant gender differences in sympathetic nervous system regulation, with sympathetic activity primarily driven by blood pressure in women and by body mass index in men.
Lambert et al. (2007) conducted an observational in Hypertension and Obesity (n=167). Hypertension and Body Mass Index vs. Normotension and lean BMI was evaluated on Muscle sympathetic nerve activity (MSNA) (p=<0.001). Sympathetic nervous activity was significantly related to blood pressure in women (37 vs 25 bursts/min, P<0.001) and to body mass index in men, with weight loss reducing MSNA only in men.
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