Population
Sprague-Dawley rats, conscious and pentobarbital sodium-anesthetized
Comparison
17beta-estradiol vs Sham-operated rats and untreated ovariectomized…
Design
Preclinical
Authors
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Supports central estrogen effects on baroreflex in rats; leaves open translation to postmenopausal women.
Estrogen enhances baroreflex-mediated bradycardia centrally by interacting with central projections of the aortic nerve in a rat model.
Mohamed et al. (1999) studied this question.
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