What question did this study set out to answer?

This study aims to evaluate the benefits of variable frequency control in cardiac pacemakers for patients with complete heart block.

July 13, 1963JAMA

Implanted Cardiac Pacemakers of Variable Frequency

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Why the study?

Does variable frequency control of implanted pacemakers improve cardiac output during exercise in patients with complete heart block?

Population

2 patients with complete heart block and implanted cardiac pacemakers

Comparison

Variable frequency control of ventricular rate… vs Fixed ventricular rate (e.g., 66 bpm)

Design

Case_series

Authors

GHGeorge J. HauptUniversity of Cologne

Discussion

Member takes

Implication

May support rate-responsive pacing for exercise output in complete heart block; leaves open prospective validation before practice change.

Key Points

This study aims to evaluate the benefits of variable frequency control in cardiac pacemakers for patients with complete heart block.
Two patients with complete heart block were assessed after receiving implanted cardiac pacemakers.
Ventricular rate was varied electromagnetically using an external induction coil.
Measurements of cardiac output and stroke volume were taken at rest and during exercise.
At rest, cardiac output remained stable across a ventricular rate of 66 to 120.
One patient exhibited increased cardiac output due to stroke volume when set at a fixed rate of 66.
Another patient showed increased cardiac output at a physiological rate during exercise, even with decreased stroke volume.

Structured PICO

Does variable frequency control of implanted pacemakers improve cardiac output during exercise in patients with complete heart block?

Population

2 patients with complete heart block and implanted cardiac pacemakers

Intervention

Variable frequency control of ventricular rate using an external induction coil

Comparator

Fixed ventricular rate (e.g., 66 bpm)

Outcome

Cardiac output and stroke volume at rest and during exercisesurrogate

Variable frequency pacing allows for physiological increases in cardiac output during exercise in patients with complete heart block.

Cite This Study

George J. Haupt (1963) studied this question.

synapsesocial.com/papers/6a20826015df8032213e8ebf https://doi.org/10.1001/jama.1963.03060020047020

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Implication

May support rate-responsive pacing for exercise output in complete heart block; leaves open prospective validation before practice change.

Implanted Cardiac Pacemakers of Variable Frequency

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Implanted Cardiac Pacemakers of Variable Frequency

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider