Key result
Myocardin is a potent transcriptional coactivator whose dysregulation is associated with diseases including heart failure, cancer, acute vessel disease, and diabetes.
Design
Review
Authors
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Myocardin dysregulation may inform cardiovascular research targets; leaves open clinical translation pending prospective studies.
This review highlights the critical role of the transcriptional coactivator myocardin in cardiovascular biology and its potential implications in heart failure and vascular diseases.
Joseph M. Miano (2015) conducted a review in Myocardin-associated diseases (heart failure, cancer, acute vessel disease, diabetes). Myocardin (MYOCD) was evaluated. Myocardin is a potent transcriptional coactivator whose dysregulation is associated with diseases including heart failure, cancer, acute vessel disease, and diabetes.
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