Key result
Increased intrinsic stiffness and adhesion of vascular smooth muscle cells, termed Smooth Muscle Cell Stiffness Syndrome, contributes to arterial stiffness in aging and cardiovascular disease.
Design
Review
Authors
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May identify a novel target in arterial stiffness; leaves open whether modulating vascular smooth muscle cell properties improves outcomes.
The intrinsic stiffening of vascular smooth muscle cells represents a novel mechanism and potential therapeutic target for arterial stiffness in aging and cardiovascular disease.
Sehgel et al. (2015) conducted a review in Arterial stiffness. Smooth Muscle Cell Stiffness Syndrome (SMCSS) was evaluated. Increased intrinsic stiffness and adhesion of vascular smooth muscle cells, termed Smooth Muscle Cell Stiffness Syndrome, contributes to arterial stiffness in aging and cardiovascular disease.
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