May 31, 2007American Journal of HypertensionOpen Access

Lack of Association Between Serum Uric Acid and Organ Damage in a Never-Treated Essential Hypertensive Population at Low Prevalence of Hyperuricemia

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Why the study?

Is serum uric acid an independent risk factor for subclinical target organ damage in never-treated uncomplicated essential hypertensives?

Population

580 subjects with recently diagnosed grade 1 and 2 uncomplicated essential hypertension, never-treated.

Comparison

Serum uric acid (SUA) levels vs Different tertiles of SUA levels

Design

Cross-sectional

Authors

CCCesare CuspidiPreventive Cardiology CVChristopher ValerioNorth Middlesex University Hospital NHS Trust CSCarla SalaGeneral Cardiology

Discussion

Member takes

Implication

No association observed does not support SUA as marker of target organ damage in early hypertension; leaves open longitudinal prognostic value.

Structured PICO

Is serum uric acid an independent risk factor for subclinical target organ damage in never-treated uncomplicated essential hypertensives?

Population

580 subjects with recently diagnosed (<1 year) grade 1 and 2 uncomplicated essential hypertension, never-treated.

Intervention

Serum uric acid (SUA) levels

Comparator

Different tertiles of SUA levels

Outcome

Prevalence of subclinical target organ damage (left-ventricular hypertrophy, carotid alterations, and microalbuminuria)surrogate

Serum uric acid does not appear to be an independent risk factor for subclinical target organ damage in recently diagnosed, never-treated patients with uncomplicated essential hypertension.

Cite This Study

Cuspidi et al. (2007) studied this question.

synapsesocial.com/papers/6a2091afd3c3af2fd9301d4e https://doi.org/10.1016/j.amjhyper.2007.01.013

Topics

Hypertension management

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Implication

No association observed does not support SUA as marker of target organ damage in early hypertension; leaves open longitudinal prognostic value.

Lack of Association Between Serum Uric Acid and Organ Damage in a Never-Treated Essential Hypertensive Population at Low Prevalence of Hyperuricemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Lack of Association Between Serum Uric Acid and Organ Damage in a Never-Treated Essential Hypertensive Population at Low Prevalence of Hyperuricemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider