Why the study?
Does hyperthyroid-induced cardiac hypertrophy alter regional capillary distribution and myocyte size in rat hearts?
Population
Normal rats and rats with hyperthyroid-induced cardiac hypertrophy
Comparison
Hyperthyroid-induced cardiac hypertrophy model vs Normal control rats
Design
Preclinical
Authors
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Rat hypertrophy data should not alter clinical practice; leaves open relevance to human hyperthyroid cardiomyopathy.
Does hyperthyroid-induced cardiac hypertrophy alter regional capillary distribution and myocyte size in rat hearts?
Hyperthyroid-induced cardiac hypertrophy in rats leads to a reduction in capillary density and an increase in myocyte size, while maintaining the regional differences observed in normal hearts.
Gerdes et al. (1979) studied this question.
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