Why the study?
Does hypertension impair coronary flow reserve in humans, and what are the mechanisms?
Does hypertension impair coronary flow reserve in humans, and what are the mechanisms?
Coronary flow reserve is impaired in hypertensive patients even before the development of left ventricular hypertrophy, driven by both increased resting flow and impaired maximal vasodilation.
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Impaired coronary reserve in early hypertension supports mechanistic studies; leaves open prognostic value and therapeutic implications.
Kozàkovà et al. (1997) studied this question.
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