Why the study?
Is coronary reserve impaired in hypertensive patients with angina and normal coronary angiograms, and is this impairment due to left ventricular hypertrophy or primary vascular alterations?
Population
43 patients, comprising 31 hypertensive patients with angina pectoris and normal coronary angiograms, and 12…
Comparison
Measurement of coronary reserve using… vs Normotensive patients (n=12).
Design
Cross-sectional
Authors
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May support microvascular evaluation in hypertensive angina with normal coronaries; leaves open causal mechanisms and therapeutic implications.
Is coronary reserve impaired in hypertensive patients with angina and normal coronary angiograms, and is this impairment due to left ventricular hypertrophy or primary vascular alterations?
In hypertensive patients with angina and normal coronary arteries, coronary reserve is significantly impaired due to primary vascular alterations rather than the degree of left ventricular hypertrophy.
Motz et al. (1991) studied this question.
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