Key result
Lithium can induce sinus node dysfunction even when serum levels are maintained within the therapeutic range.
Highlights that lithium-induced sinus node dysfunction can occur even at therapeutic serum levels.
May warrant ECG vigilance in lithium users irrespective of levels; leaves open incidence and causality in larger cohorts.
Lithium is used as an antimanic and mood-stabilising drug. It can cause various adverse effects such as nausea, vomiting, polyuria, fine tremors, myocarditis and arrhythmias. We are describing a case of lithium induced sinus-node dysfunction in a patient with serum lithium levels in therapeutic range.
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Shetty et al. (2013) studied this question. Lithium can induce sinus node dysfunction even when serum levels are maintained within the therapeutic range.
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