Key result
Patients with atherosclerotic renovascular hypertension had significantly higher baseline adjusted pulse wave velocity than those with essential hypertension (12.8 vs 11.6 m/s; P=0.029).
Why the study?
Does stenting combined with multifactorial drug therapy reduce arterial stiffness in patients with atherosclerotic renovascular hypertension?
Cohort (n=81)
Does stenting combined with multifactorial drug therapy reduce arterial stiffness in patients with atherosclerotic renovascular hypertension?
Absolute Event Rate: 12.8% vs 11.6%
p-value: p=0.029
In patients with atherosclerotic renovascular hypertension, stenting and multifactorial medical therapy reduces central blood pressure and augmentation index, but does not improve pulse wave velocity over 6 months, likely due to irreversible structural vessel changes.
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Higher baseline arterial stiffness in atherosclerotic renovascular hypertension signals advanced remodeling; leaves open whether stenting improves pulse wave velocity.
Fodor et al. (2014) conducted a cohort in Atherosclerotic renovascular hypertension (n=81). Atherosclerotic renovascular hypertension vs. Essential hypertension was evaluated on Adjusted pulse wave velocity (PWV) at baseline (p=0.029). Patients with atherosclerotic renovascular hypertension had significantly higher baseline adjusted pulse wave velocity than those with essential hypertension (12.8 vs 11.6 m/s; P=0.029).
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