Key result
Resistant hypertension was associated with significantly higher augmentation index and pulse wave velocity (P<0.01) and lower aortic strain and distensibility (P<0.01) compared to controls.
Why the study?
Is resistant hypertension associated with increased arterial stiffness compared to controlled hypertension and normotension?
Population
87 patients, including 30 with resistant hypertension, 29 with controlled hypertension, and 28 normotensives
Comparison
Resistant hypertension vs Controlled hypertension and normotension
Design
Cross-sectional
Authors
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Supports resistant hypertension–arterial stiffness link; hypothesis-generating, leaves causality open and should not change practice.
Cross-Sectional (n=87)
Is resistant hypertension associated with increased arterial stiffness compared to controlled hypertension and normotension?
p-value: p=<.01
Resistant hypertension is associated with increased arterial stiffness compared to controlled hypertension and normotension, suggesting a potential role of arterial stiffness in its pathogenesis.
Pabuccu et al. (2011) conducted a cross-sectional in Resistant hypertension (n=87). Resistant hypertension vs. Controlled hypertension and normotension was evaluated on Arterial stiffness (augmentation index, pulse wave velocity, aortic strain, and aortic distensibility) (p=<.01). Resistant hypertension was associated with significantly higher augmentation index and pulse wave velocity (P<0.01) and lower aortic strain and distensibility (P<0.01) compared to controls.
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